777 flies to most continents within the route structure, so it goes from 1.25 hour Riyadh trips to 16.5 hr trips to LAX. But there is no guarantee that it will stay on any medium haul European route, it has already lost Manchester and half of the Paris flights to the 787.
Gone are the days when Flight Operations management dictated which aircraft flew which route based on their desire to frequently visit that destination for personal reasons.