I did that route quite a few times, with GVA-LHR and SYD-CBR connections. In the end, for me, doing the entire journey in one go was best. Breaking it up with a day or two in BKK or SIN was the worst. Can't imagine a DXB routing either. One medium and one ultra LH wouldn't appeal to me.
I certainly wouldn't do any of the above in Y though.