The distractions on the guard frequency are usually genuine urgency calls. As professional pilots we should know how to deal with this. Whenever I feel distracted by calls on 121.5 I turn the frequency down low enough so not to disturb my active ATC frequency, but high enough for me to notice that someone is calling me should all go a bit quiet. Usually the volume will be back at a normal level well before that anyway.
Like many I cannot comprehend why someone would want to make animal noises on 121.5 but I think we all know more or less where this behavior comes from geographically. As I stated earlier, just ignore it. Don't feed the troll. You can't tell a pig not to roll in its own
As for the practice PANs, well, you just cannot complain about distractions and endorse practice PANs in the same topic