The same way you would have had hundreds of controllers run non-radar E back in 2004 when the mighty NAS 2b (was it) was going to be introduced, and exactly the same way every controller in the world used to run controlled airspace before radar: procedurally. I'm surprised at your lack of understanding of basic ATC principles, Dick.
The good thing about C is that it captures VFR. VFR Metal is just as unforgiving as IFR Metal... E airspace doesn't make the collision any softer or indeed make the VFR "go away".