The hour was unsociable, but a 4-hour return is more or less a 'Home to Southern Spain/Greece and back' from where I'm based. That's not big, that's actually a rather relaxed day out and done by the thousands every single day.
These duties that have people doing in excess of 8 hrs airborne with two sectors are asking for trouble if they are rostered several in a row month in month out, year on year.
If you are 28, no kids, a girlfriend lives down the road, have the option of getting into bed and dozing off when you finish work without all the hustle and bustle of a normal family household, then it is tiring but safely achievable. If on the other hand you are 42, have two kids under five, a wife that has to work around your alarm clock settings and random absence during public holidays and weekends etc etc, then it is a case of family v's health v's work and something has to give. There is no free lunch with this type of rostering.