I may have missed it, but has anyone so far pointed out the other problems that a loss of pressurization, especially an RD or ED, involves? Bends, chokes, trapped-gas dysbarisms, CNS.... taking a few hundred people, not all of them healthy, from 3000ft to 40,000 feet in a few seconds is going to create all kinds of physiological havoc that calls for descending to a lower altitude ASAP.