I started out with a two blade McCauley C23 on my Bonanza, seven years later switched to a C76 with prop deice (3 blade). Less noise, less vibration, less top cruise, slightly better take-off performance, higher overhaul costs. I am now on a Hartzell 3 blade Q-tip, much less noise, even less top cruise, low landing fees when in Germany.
My friend switched from a C76 3 blade McCauley to a 3 blade Super Scimitar, unable to tell because he added a turbonormalizer at the same time. Very good prop.
Another friend switched from a Hartzell 3 blade to a C406 3 blade; Very bad decision because it moved the CG aft a lot because the new prop was lighter, needing lots of lead in the nose to get it right.
Depending on aircraft type, prop weight needs to be considered as well.