I did land a B777 sim successfully by hand the first time (well, survivably) BUT I had a 777 first officer (a friend who had arranged the sim slot, similarly in the small hours) in the right hand seat. Without him the systems would have overwhelmed me, and I'd probably have lost control chasing them. As it was I was able to concentrate solely on the hand flying. He also gave me speeds &c.
I wish I'd tried it with him only on the intercom to simulate ATC trying to talk me down. I don't think I'd have made it.
Best part was flying the 777 under the Verrazano Narrows bridge...