MAN-JFK/EWR
This has been something of a sucess story of 2015.
In 2014, around 226k PAX travelled between MAN and either JFK (112k) or EWR (114k).
In 2015, that number had jumped to 343k. EWR held roughly steady at 111k but JFK jumped to 232k.
With further increases in frequency from TCX and with the U.S. carriers putting on larger aircraft this will hopefully continue to grow strongly.