Hi GMR,
Welcome to PPRuNe.
I say go for it. Yes, the 182 is a "busier" and heavier aeroplane, but with your previous 172 experience, you should find it quite familiar. Handling the cowl flaps and the prop will take a little while to get comfortable with, but you will have your instructor with you to remind you.
As long as you trim properly, low-speed handling is not an issue.
I recommend that at some stage, you do some dual flying at gross weight, to get comfortable with the handling and performance changes.