Those are Windows programs and you're using a Mac so you can't install them without first installing Windows in some form.
Two alternatives: setting up a dual boot system where you install Windows on a separate partition and choose to boot either OS X or Windows when you start (or reboot) the computer. Not an overly convenient solution because you can only use one operating system (OS X or Windows) at a time.
The other alternative is to install Windows in a virtual machine (a virtual computer running in software) and run that within OS X. Far more convenient as you're using both operating systems at the same time but it affects system performance (may or may not be an issue depending on your hardware).
The caveat is you need to have a suitable copy of Windows available to install complete with its own licence key.
There is also Crossover which can run some Windows software directly in OS X but you're out of luck with Flight SIm and no idea about Rant.