Be cautious if its turbocharged as some were time limited at max and there is also the danger of overboost
In a Seneca I used to experiment and on a very long runway set climb power for take off then didn't touch it for takeoff, climb, or cruise.
It was quite smooth for the PAX as there were no power noise changes
But it was just experimenting and not a realistic way of operating.
On a normally aspirated engine always be aware of leaning some high altitude airfields you need to lean for takeoff so always lean as it will always find its level even if leaning ends up as full rich
I think there has always been a reluctance to Lean probably from training days when instructors were scared students might stop the engine and scare themselves or overleen and damage it!
Pace