You are welcome.
The Twin Otter has a lot of rudder and elevator authority at low speed so don't be afraid of using full deflection if needed.
I flew those airplanes on both wheels and floats, it was fun to the last day.
The place I worked for had 2 go off the runway:
The first one was caused by a new Captain with no time in the DHC-6, he just screwed up.
The second was an attempt to take off with full flaps, the main wheels lifted off and the nose wheel stayed on the ground like a wheel barrow, they veered off to the left and hit the glide slope shack for runway 8 at San Juan airport in Puerto Rico.
The moral of the story is to use full aft elevator control if you try to take of with full flaps.