If the photos, ADS-B and FR24 data posted on this forum are anything to go by, it looks very much that the aircraft suffered a catastrophic event in the cruise. Perhaps brought about from a major fuselage rupture from an internal or external force.
With the TWA 800 crash, initially there was a big flap that it had been shot out of the sky by a rogue missile. In the final outcome it was attributed to the center fuel tank.