I've had several occasions in the last few days, where consideration of wake turbulence was necessary for safe flight, both landing behind, and taking off after another aircraft. In the case of landing (behind a departing Dash 8) I recognized it as being appropriate to land short, and be firmly on the ground before its rotation point. In a few other cases, considering the crosswind, to assure all of my operations were upwind of the location of the expected wake.
As long as you are comfortable about list moment maneuvering, it's entirely fine to approach or depart offset to the runway centerline, to avoid a wake turbulence area.