Back in 1979 a Braniff B-747 PIC had a heart attack and died. Crew decided there was no need to divert to the nearest airfield (LAX) and cause problems for the 331 passengers, so they flew on to the destination (DFW). The pilot's wife was one of the cabin crew.
Article here:
https://news.google.com/newspapers?n...,2362847&hl=en
https://news.google.com/newspapers?n...,2362847&hl=en