It is possible to touch down on, and hold only the upwind wheel on the surface, though this is a rather extreme demonstration.
I remember the first time I landed an Ercoupe in a strong crosswind, I was really worried, as it had no rudder pedals. I had no choice, I just flew the centerline, and it all figured itself out as I touched down. Since, I have found it easier to just fly the plane, and not worry so much about the details of
how I did it.