LOGICAL, it would be just under three hours flying in a Dornier 228 to London which would likely be neither comfortable nor profitable (bear in mind airport fees on the other end). Aurigny looked at sending a 228 into London City last year and assessed that it would be so costly that they waited until they could firm up the lease on an ATR 42.
Much more likely that a gap would be found in the new Twin Otters' schedule to operate from Glasgow, or (more likely still) that Skye would be added to the existing Hebridean operation out of Connel.