"You might not hesitate to put TP pilots in a 777 or a 380 but the insurance premiums will surely go through the roof. "
Complete BS... No insurance company gives a crap about the background of your crew. If they are trained and approved according to the airlines standard then they are considered good enough for the insurance companies.
TP pilots would lack the long haul experience but the TP pilots are not coming as DEC so that won't be a big issue.