Of course. there was a precedent:
ASN Aircraft accident Douglas DC-6B F-BIAO Mt. Cameroon
The Air Afrique flight took off from Douala runway 12 at 13:16 GMT on an IFR flight plan to Lagos, cruising altitude 16500 feet. Last radio contact was with Kano at 13:25 when the crew estimated leaving the FIR around 13:38. Two minutes later the aircraft struck Mount Cameroon in a straight climb at 6500 feet (800m below the peak).
PROBABLE CAUSE: "The accident was caused by a lack of caution on the part of the pilot-in-command who deliberately selected a route which led the aircraft into a dangerous and even prohibited sector at too low an altitude. Also, he neglected his navigation and transferred to instrument flight when approaching the mountain range."