Centaurus: During training, this was a question of mine as well. I was told the trim was set with V2 initial climb (all engines) being the certification (and subsequent SOP) target. I was also told that optimum stab trim settings will always require nose up input.
As to the secondary discussion here, it is interesting to hear theories on the need for additional back stick at around 9-10 degrees pitch. I believe the phenomenon occurs on most if not all transport category aircraft although the DC-9 does not require nearly as much additional back pressure as those aircraft I've flown with conventional tailplanes. Ground effect and wing downwash are the two theories I have heard over and again, but never has there been a definitive answer, although the aerodynamicists I've talked to favored GE as the cause for the 'pause.'