I'm sure they'll try and eliminate the pilot somehow, and hopefully fail... In all honesty I believe that things will be pretty much as they are now; ok 777's will be old hat and the EFIS displays and the cockpit generally will become even more user friendly but I reckon unfortunately that the pilot will be there simply to monitor the aircraft. By that I mean monitoring the computer doing the take-off/route/landing all by itself. Even the ATC and navigation (changes/diversions etc) will probably be done via data links to satellites etc... I don't like this idea myself, but I can see this being the likely route commercial aviation will take.
I firmly believe that the F in flying was meant to stand for Fun, as such there maybe a chance of this vanishing in commercial aviation. But there will always be smaller regional airlines that will be slower to embrace this technology due to cost, so there will be a place for more hands-on pilots. Plus you may get the opportunity to do tourist flights to the Moon, you never know. (Mars?) Plus there is Nasa trying to make flying body aircraft that skip over the atmosphere, that could be common by then.
Providing that flying does not continue to become elitist (i.e. more expensive), I reckon all pilots should be relatively safe in 30/40 years or so...
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