For most routes and carriers the A380 is just too much plane. It also has a problem that the hold is full of pax baggage, so not enough room for (lucrative) cargo. So the A380 is limited to pax heavy/cargo light routes.
Which makes you wonder why they were built in the first place. Perhaps one day there will be a cargo version similar to the AN225 that will make money.
MAS's problems will be compounded when BA restart KUL with the 787. Interesting times ahead for MAS