I just line the green track diamond up with the ILS course marker on the PFD, go for 800 FPM at the start of the descent and fine tune from there. I rarely fly with the bird these days unless NPA requires it. You do get some IR drift but once you've figured it out you just target 1-2 degrees left/right of the marker.
Flap 2 is less of an issue when flying manually as you can stuff the nose down yourself, flap full tends to catch people out more.
For thrust, go for the gross weight + 5 ballpark figure then rely on the speed trend arrow. Worth a glance at the N1 setting from time to time to make sure they're balanced.