JeroenC
Depending on what aircraft in the sim, you could check out the Aeroperu 603 accident. Static port blockage caused erroneous altitude and airspeeds. Altitude was sent to ATC via transponder - ATC believed the aircraft was well above terrain but the aircraft crashed into the ocean a while later.
If I remember correctly this was a B757 or B767. Wikipedia has more information, I'm sure.
Last edited by MrSnuggles; 16th Mar 2015 at 16:00.
Reason: correcting company name