Glad rag - It might be possible once but it would be a short flight.
While we're all used to PowerPoint-vs.-real loadouts, it's quite difficult to get to the F-35's alleged 18,000 pounds. You have 11 stations, which looks impressive, but one is gunpod-only (maybe other non-droppable items later), four are single-purpose (2 x AIM-120, 2 X SRAAM), two are size-constrained and only two are wet.