I once had to carry out a single engined takeoff, transit and landing in a Puma HC1. We practiced minimum power takeoffs quite regularly so I had no real qualms about it, other than that it involved a sea transit. This type of flight had to be approved by the Air Officer Commanding. He willingly gave verbal authorisation in person for it, not surprising seeing as we were on our way to get a serviceable aircraft to fly himself and entourage back to the mainland.
I agree with previous posters about some modern medium twins being very capable on one engine. Having taken off on two, I shut down the one with the stuck oil cooler thermo valve then started it up again for a twin engined landing. It would easily have managed the entire trip on one, far better OEI performance than the old Puma (which didn't have a lot, tbh).