I'm a former airline guy turned corporate...
I spent 15 years airline with decent schedules, mostly 4 on 3 off or 3 on 3 off and able to drive to base. City pairings were varied enough that I didn't have everything memorized but they were all familiar, some more than others.
I had the opportunity to switch to corporate a few years ago. I'm on call all the time unless on leave. I average 9-10 days away a month so I have more time off than before. I enjoy the extra time at home more and the ad hoc nature of the operation. I feel more challenged in some ways than before in the airline world.
Even though I have more time off my wife and kids miss knowing when my days off are going to be.
I stay in nicer hotels now and eat better on the airplane. All in all I'm happier with my corporate job and my wife misses the airline schedule.
Horses for courses.
OP