On arrival at the hotel does the co-pilot:
a. Arrange for the imprest to be left in the hotel safe deposit box
b. Place the imprest in the hotel room safe, whilst being protected by the other crewmembers until it is secure
c. Leave it in his nav bag on the aircraft
d. Get changed in a rush, shove a few extra $100 bills in his pocket for later on in the club, stash the rest in his unlocked samsonite, get drunk, hand out the cash liberally to the crew in the club/strip joint, and all crewmembers agree they'll sign for it in the morning, then denying they were ever in the club on the first sector of the day, before agreeing on the second sector that they possibly were, but could never have spent that much cash.