Well you can see why the military might be interested as the crew plus seats and support are proportionately heavy and g limits could be stretched. The military business case would still be for human ground control fairly obviously. Key issue probably link capacity and integrity. For civilian freight or heaven protect us pax, never - it is not a technology thing primarily, just plain obvious commercial pay back.
Imagine an autonomous system having to deal with unusual attitude recovery. A successful and reliably performing system may well be a technical impossibility when you stretch to ten to the power of whatever. No doubt a big button which called up an automatic recovery sequence would be quite welcome but imagine the permutations of starting conditions, data reliability, aerocharacteristics out of envelope etc.
Anyway, as pax, I derive a certain comfort knowing that those in control are mortal and have skin in the game!