Win ME does have a few more MultiMedia instructions so Entertainment Applications should run better. But that doesn't interest me and the only bit of ME I liked was the Restore function, which you now get with XP.
No, I took ME off my little Sony Vaio Picturebook and put Win 2K on. It was a struggle with some of the Hardware but Sony did provide all the Patches and Updates and it hums along now.
I agree, get rid of it and go forward if you can. Otherwise Win 98SE is good but, like all Bill's OSs, it has few quirks with modern hardware.
The great advance along the NT chain of OSs (NT4, Win 2K and XP) is the Hardware Abstraction Layer (HAL) that protects the Kernel from hardware incompatibilities and idiosyncracies. Thus you get many fewer hardware crashes and problems.
There was great hilarity in the Fobotcso Towers when I first told Mrs fob about my new Hardware Abstraction Layer and I 've never been allowed to forget it.