Thunderball, in the words of Fermi....if they existed, they'd be here. If there was any niche for a UK based freight 747 operator the market would have supplied one. The UK aviation environment does not lend itself to competing against fly by nights like MK, and with the mandatory upgrades of navigational equipment together with the strict regulatory regime there is little if any incentive to start up from UK.
Yotter....it depends on your point of view