Alcohol dulls the senses, impairs reaction time, makes motoric movements and reflexes slower. It's poison for the brain, and I'm not going to defend any drunk driver. Yet, as some correctly pointed out, alcohol is not a major cause of concern for airline accidents. It's a potential problem that people are well aware of, and airlines have an excellent track record of managing it, without the help of the police. Then...there's the issue of fatigue, which is just as dangerous, and in real life, a bigger threat, yet, methinks it gets less attention than alcohol.