In an American-powered single (or any with RH prop rotation) of say 450 hp or more, a left crosswind can be quite a challenge. The combination of "torque" (actually the propwash vortex pressing the LH side of the fin) plus the x-wind (more of the same) can send you off the left side of the r/w into the weeds - or the ditch.
Awareness is the preventive action; be prepared to use more right rudder than usual, and open the throttle slower, so the powerplant doesn't get ahead of the rudder control authority.
And it would take a really really strong wind to create the situation jcomm describes.