Is it permanent OML or is there a chance to get it removed after a number of years? I have heard of people having had concussion from accidents etc being given an OML with the chance to be reassessed and have it removed after 5/10 years.
In theory of course the OML will not stop you being able to do airline work as it is by nature multi pilot ops. I have seen a few advertised jobs that require a medical with no limitations, but more often than not this is not mentioned. Whether or not it would matter to an employer when decided who to hire etc probably will depend on the person hiring.
One thing to think about is the possibility that instructor may not need to be ruled out. A PPL can instruct on a class 2 medical so you should be able to instruct that way. Whether or not the OML restriction causes further requirements I do not know, but might be worth looking in to.