Joe, if you mean from EDI to Mumbai or Delhi, I can't see how, where is the market? I understand the largest Indian community in Scotland isn't in Edinburgh, but even then its doubtful if a route could be supported.
IMO Virgin's best way forward, certainly in Scotland, is a part or full week based aircraft, developed like Manchester, with MCO LAS JFK BGI as destinations. The 744 is too big, the 789 might be ideal, in a LGW style configuration. JFK would link with Delta's network.
Though sadly, I think this may never happen given the current uncertainty.