Creampuff - perhaps you should direct that question to one of your mates at CASA. I'm sure they can give you a far more comprehensive answer than I could.
But I thought you had expertise in this area, ausdoc.
Surely if there is "recent medical research" that "indicates that the safety-related implications of an individual’s CVD may be more significant than they were initially considered to be", the research would be published and a person with your expertise would be aware of it and be able to cite and quote from it.
Given the profound consequences for the careers of pilots and aspiring pilots, and the disruption caused by the correspondence with AOC holders, CASA would not merely invent or exaggerate the implications of some "recent medical research". That would not only be intellectually dishonest: it would be unlawful.
It is passing strange that CASA has yet to quote one syllable from the recent medical research to which CASA refers, to support the assertions made by CASA about the implications of that research.