Oh c'mon guys, get real. Lets say you are looking at the forecast (forecast, note) for 1200z. What time are you flying? 1200z? No, thought not.
These things are to give you an idea of how the atmosphere is expected to behave in a general sense. Not to give you an accurate wind vector for flight navigation purposes.
For navigation you'd be better off looking at the ground wind at the start of your flight and making the speed and direction adjustment for winds aloft. Please, at least do this to check that what the F214 told you is still right.