Personally I will not fly single pilot IFR without and operating two axis autopilot and at least a portable GPS with a moving map display.
The autopilot lets me keep the big picture without having to mind the airplane every second and the GPS gives me accurate real time situational awareness.
The last time I flew an NDB approach in for real IMC conditions without some sort of GPS to provide final approach track guidance was 1994.
I teach for the IFR rating so I can certainly fly a stand alone NDB airway/hold/approach, but you have got to be barking mad to think that I would actually go and do that for real, when better technology exists.
Bottom line
for pilots have been properly trained and work at fully understanding the electronic magic and maintaining their skills modern technology makes flying easier, better and most importantly safer.