Most airliners are now using 4000 or even higher, to save weight.
The hydraulic system will not have enough flow to cause the door to pop off, but a compressed air system might, but I don't think the 757 uses one, in that area at least.
A catastophic failure of an outflow valve might give enough over pressure
I appreciate there isn't really a lot to do in your location, at night, but even by R n N's "fly sim analysts speculation " standards, the above is a an outstanding effort.
The "door" being a wing panel, for a start, and then, the little matter of the outflow valve.
If you could provide a schematic of the, lets call it the cabin pressurisation system, that shows how the outflow valves now affect the wing structure and upper surface in particular in this case, this may well be of interest to many for whom this development is a revelation.