there is a track consideration, but not regulatory in nature
Regulations (pertinent to the jurisdiction) come into play and dictate minimum terrain clearance requirements within defined splays which, in execution, involves the hills, valleys and where the aircraft might seek to track .. just how the detail might be achieved, though, lies within the province of the operator's in house or contracted ops engineering folk. Nothing terribly difficult there .. but it does require good housekeeping and attention to detail.
It is worth keeping in mind that regulations are ALWAYS a minimum standard, whether that be design or operations ...
Given that regulations are minimum standards, the more stringent consideration should always be that of corporate governance and risk management. One might like to think that an operator seeks to operate to a standard somewhat higher than the minimum regulated.
At the end of the day, given that getting this stuff very wrong may/will have very public consequences .. simple commercial longevity suggests it ought to be of some importance within the corridors of corporate power ..