A catastrophic failure of the fuselage, perhaps due to these supposed cracks near the GPS antenna, could lead to the rapid break up of the aircraft.
The explosive decompression and rapid onset cluster of system failures would overwhelm the best of us.
35'000' would give useful consciousness of about 20secs, probably insufficient for meaningful diagnosis and response.
No large pieces would make tracking by primary radar difficult.
I'd be looking for wreckage in a plume downwind of the last known position. Didn't see the high level chart, but I'm guessing that the seasonal jet would be westerly at 60-90 kts at that position?
Perhaps someone could enlighten us?