Originally Posted by
updrifter
Aside from the Payne Stewart Learjet incident there has been another prominent case of crew and PAX being knocked out by hypoxia. Helios Airways flight 522 in 2005, a Boeing 737.
https://en.wikipedia.org/wiki/Helios_Airways_Flight_522
The problem was simply that the pressurisation system was set to "manual" instead of "automatic". The 737 flew on auto until fuel was empty and crashed.
In case of MH370 I wonder where it would have ended up in such a scenario. For sure it would have gone far, but it should have attracted attention somewhere on the way?
Hypoxia would not switch off the ADS and SSR transponders. In all the cases of hypoxia and crew incapacitation I have read, the aircraft carried on with no problem squawking as normal. Just no-one answered the RT.