I believe the Israelis are flying modified pilot-less biz jets for special missions for some time now.
In fact operated one into one of the busiest airports in the world just the other day.
I see no problem with an airliner being automated.
When was the last time anyone flew the aircraft themselves, with out a/t, a/p, a/l and a/b?
I would have no problem with a pilot-less a/c.
I had a friend enter a cockpit the other month this very topic came up, the cheeky guy turned around and said where is the auto fix button?
I love automation