Yes, but to travel by train from Edinburgh or Manchester to Ostend involves two train changes and a change of stations as there are no Eurostar services north of London. I travelled from Irvine to Ostend by train a couple of years ago. The journey took about 15 hours start to finish. Even the journey from Charleroi Airport took several hours with most of my time spent waiting on my next connection. I would definately fly into Ostend given the chance and probably go there more frequently if the journey was much less arduous. However, I don't know how sucessful a low cost point to point service would be.