Engine caught fire on a 707 one night over the Middle East, extinguished and diverted to the only practical airport available, and arrived to find it was now raining and the ILS was u/s. (GPS/INS not yet invented )
Murphy was alive and well.
Ended up doing a manual, visual, NDB approach at night and broke out just above minima - on three.
But then we only had a rudimentary auto-pilot and auto-throttle anyway, so it was really - almost - just another day at the office.
No problem.