I don't see the value of arguing between two vs four when considering the subject event (neither an incident nor an accident in my book).
The consideration is mostly the risk of anything else going wrong either dependently or independently and its probable effect on the flight.
It seems that almost all of us focus solely on the remaining engines and their probability of failure. Although I've not seen any comments assessing the impact on a 5 hr flight should a second engine fail on a quad.
I'm not prepared to take sides in what-if arguments of this kind since all the data I've seen regarding independent failures in cruise says that at worst it's an extremely small contributor to overall in-flight risk for all fleets.