Most probably yes. Even a little bit icing on wings dramatically increases drags/reduces lift, taking-off before aircraft is completely de-iced is also prohibited. I know an accident about that, a Canadian Fokker F-28 instantly stalled after take-off in 1989.
Saab 340 and F-28 are really quite different in their stall characteristics. Fat straight wing Saab can handle bit of ice. The F-28 ( and DC-9-10srs), not so much.