the ILS localiser, used to guide aircraft in the end of the runway, projects a fan-shaped beam with an azimuth angle of five degrees at its apex.
That five degree fan is the area in wich the localizer signal can reliably be received by the equipment on the aircraft. The target then is to fly down the centre line of that fan, any deviation from that will show in the cockpit and be quickly corrected.
The direction of that transmitted centreline is fixed at installation of the system and in the majority of cases it is pointing down the extended centreline of the runway the system is guiding aircraft to. ILS systems can be installed at an angle from a runway, but that is only done where terrain or other obstructions require it and that offset-angle is then fixed as well and cannot be changed without physically moving and realigning the antenna-array.
In theory it would be possible to instruct crews to fly the localizer at a constant deflection of x and thus follow not the line the transmitter is pointing at but come in at a slant. I believe that is never done.
You would need multiple ILS system installation to the same runway to achieve any noticeable spread of flight paths at that stage. That is never done either.