In 10 years time, either the 737 Max or A32X NEO (and hopefully both) will be flying. East coast airports are easily within range from SNN, ORK etc.
Even at the moment, a 737-900ER could comfortably do Boston. While JFK is theoretically in range, the incidence of tech stops would make it unlikely.
Should the 737 Max/A32X NEO become an aircraft of choice, it could potentially be interesting as you could then see the same aircraft type used for transatlantic and short-haul operations.